HEADING WAY UPTOWN: Macy’s is eyeing Harlem to open its first uptown store, although no deal has been signed. “We are always looking for opportunities but we never say where we are looking or where we may not be looking,” said Jim Sluzewski, Macy’s Inc. spokesman. One possibility is a 31,000-square-foot vacant lot on the southwest corner of Lenox Avenue and 125th Street, which stretches the entire block from 124th to 125th Streets. Macy’s reportedly checked it out but had no luck securing some adjacent buildings, which would have provided a bigger footprint for a store. Macy’s is said to be continuing to search the area, however. There is also a smaller empty lot next to the Apollo Theater and a vacant lot on Park Avenue and 125th Street where there is less pedestrian traffic. The 125th Street corridor is filled with small, moderately priced independent shops, discounters and street vendors. But in the past few years there has been an influx of chains, notably H&M, Body Shop, MAC, Old Navy and Aerosoles, and big boxes will sweep in next year with the opening of East River Plaza, under construction off the FDR Drive between 116th and 119th streets. Best Buy, Target, Home Depot and Marshalls have signed on.